Séminaire Mind Your Language - Investigating semantics above and beyond language: a clinical and cognitive neuroscience approach

Résumé (anglais) : The ability to build, store, and manipulate semantic representations lies at the core of all our (inter)actions. Combining evidence from cognitive neuroimaging and experimental neuropsychology, I study the neurocognitive correlates of semantic knowledge in relation to other cognitive functions, chiefly language. In this talk, I will start by reviewing neuroimaging findings supporting the idea that semantic representations are encoded in distributed yet specialized cortical areas (1), and rapidly recovered (2) according to the requirement of the task at hand (3). I will then focus on studies conducted in neurodegenerative patients, offering a unique window on the key role played by a structurally and functionally heterogeneous piece of cortex: the anterior temporal lobe (4,5). I will present pathological, neuroimaging, cognitive, and behavioral data illustrating how damages to language-related networks can affect or spare semantic knowledge as well as possible paths to functional compensation (6,7). In closing, I will discuss our ongoing work on form-meaning mapping across demographic variables and neurological conditions, as well as our radically comparative approach between animals, humans, and machines (8).

Références :

[1] https://doi.org/10.1016/j.neuroimage.2016.08.068 

[2] https://doi.org/10.1162/jocn_a_01328

[3] https://doi.org/10.1162/jocn_a_01390

[4] https://doi.org/10.1016/j.cortex.2019.01.006

[5] https://doi.org/10.1016/j.nicl.2020.102369

[6] https://doi.org/10.1093/brain/awaa212

[7] https://doi.org/10.7554/eLife.63905

[8] https://doi.org/10.1038/s41597-023-02015-3 

Site web : https://valentina.borghesani.org/