Publications de WAKING

Voir le site HAL des publications de l'équipe



  1. Guindon J, Lin JS. Inflammatory pain models with capsaicin or glutamate injections: are they comparable and reproducible? Clin Exp Pharmacol Physiol (2014) 41(12): 947-949.
  2. Guyon A, Balbo M, Morselli LL, Tasali E, Leproult R, L'Hermite-Baleriaux M, Van Cauter E, Spiegel K. Adverse effects of two nights of sleep restriction on the hypothalamic-pituitary-adrenal axis in healthy men. J Clin Endocrinol Metab (2014) 99(8): 2861-2868.
  3. Inocente CO, Gustin MP, Lavault S, Guignard-Perret A, Raoux A, Christol N, Gerard D, Dauvilliers Y, Reimao R, Bat-Pitault F, Lin JS, Arnulf I, Lecendreux M, Franco P. Depressive feelings in children with narcolepsy. Sleep Med (2014) 15(3): 309-314.
  4. Inocente CO, Gustin MP, Lavault S, Guignard-Perret A, Raoux A, Christol N, Gerard D, Dauvilliers Y, Reimao R, Bat-Pitault F, Lin JS, Arnulf I, Lecendreux M, Franco P. Quality of life in children with narcolepsy. CNS Neurosci Ther (2014) 20(8): 763-771.


  1. Aydinoz S, Huang YS, Gozal D, Inocente CO, Franco P, Kheirandish-Gozal L. Allergies and Disease Severity in Childhood Narcolepsy: Preliminary Findings. Sleep (2015) 38(12): 1981-1984.
  2. Bastianini S, Silvani A, Berteotti C, Lo Martire V, Cohen G, Ohtsu H, Lin JS, Zoccoli G. Histamine Transmission Modulates the Phenotype of Murine Narcolepsy Caused by Orexin Neuron Deficiency. PLoS One (2015) 10(10): e0140520.
  3. Carlos C, Hageman J, Pellerite M, McEntire B, Cote A, Raoux A, Franco P, Rusciolelli C, Consenstein L, Kelly D. Neonatal intensive care unit discharge of infants with cardiorespiratory events: Tri-country comparison of academic centers. J Neonatal Perinatal Med (2015) 8(4): 307-311.
  4. Dissel S*, Seugnet L*, Thimgan MS, Silverman N, Angadi V, Thacher PV, Burnham MM, Shaw PJ. Differential activation of immune factors in neurons and glia contribute to individual differences in resilience/vulnerability to sleep disruption. Brain Behav Immun (2015) 47: 75-85.
  5. Lecendreux M, Lavault S, Lopez R, Inocente CO, Konofal E, Cortese S, Franco P, Arnulf I, Dauvilliers Y. Attention-Deficit/Hyperactivity Disorder (ADHD) Symptoms in Pediatric Narcolepsy: A Cross-Sectional Study. Sleep (2015) 38(8): 1285-1295.
  6. Poisson A, Nicolas A, Cochat P, Sanlaville D, Rigard C, de Leersnyder H, Franco P, Des Portes V, Edery P, Demily C. Behavioral disturbance and treatment strategies in Smith-Magenis syndrome. Orphanet J Rare Dis (2015) 10: 111.
  7. Poisson A, Nicolas A, Sanlaville D, Cochat P, De Leersnyder H, Rigard C, Franco P, des Portes V, Edery P, Demily C. [Smith-Magenis syndrome is an association of behavioral and sleep/wake circadian rhythm disorders]. Arch Pediatr (2015) 22(6): 638-645.
  8. Thimgan MS, Seugnet L, Turk J, Shaw PJ. Identification of genes associated with resilience/vulnerability to sleep deprivation and starvation in Drosophila. Sleep (2015) 38(5): 801-814.
  9. Thiriez G, Mougey C, Vermeylen D, Wermenbol V, Lanquart JP, Lin JS, Franco P. Altered autonomic control in preterm newborns with impaired neurological outcomes. Clin Auton Res (2015) 25(4): 233-242.
  10. Urbain N, Salin PA, Libourel PA, Comte JC, Gentet LJ, Petersen CCH. Whisking-Related Changes in Neuronal Firing and Membrane Potential Dynamics in the Somatosensory Thalamus of Awake Mice. Cell Rep (2015) 13(4): 647-656.
  11. Vinck M, Bos JJ, Van Mourik-Donga LA, Oplaat KT, Klein GA, Jackson JC, Gentet LJ, Pennartz CM. Cell-Type and State-Dependent Synchronization among Rodent Somatosensory, Visual, Perirhinal Cortex, and Hippocampus CA1. Front Syst Neurosci (2015) 9: 187.


  1. Bastianini S, Lo Martire V, Berteotti C, Silvani A, Ohtsu H, Lin JS, Zoccoli G. High-amplitude theta wave bursts characterizing narcoleptic mice and patients are also produced by histamine deficiency in mice. J Sleep Res (2016) 25(5): 591-595.
  2. Duchene A, Perier M, Zhao Y, Liu X, Thomasson J, Chauveau F, Pierard C, Lagarde D, Picoli C, Jeanson T, Mouthon F, Dauvilliers Y, Giaume C, Lin JS*, Charveriat M.* Impact of Astroglial Connexins on Modafinil Pharmacological Properties. Sleep (2016) 39(6): 1283-1292.
  3. Franco P, Junqua A, Guignard-Perret A, Raoux A, Perier M, Raverot V, Claustrat B, Gustin MP, Inocente CO, Lin JS. High bicarbonate levels in narcoleptic children. J Sleep Res (2016) 25(2): 194-202.
  4. Parmentier R, Zhao Y, Perier M, Akaoka H, Lintunen M, Hou Y, Panula P, Watanabe T, Franco P, Lin JS. Role of histamine H1-receptor on behavioral states and wake maintenance during deficiency of a brain activating system: A study using a knockout mouse model. Neuropharmacology (2016) 106: 20-34.
  5. Perrenoud Q, Pennartz CM, Gentet LJ. Membrane Potential Dynamics of Spontaneous and Visually Evoked Gamma Activity in V1 of Awake Mice. PLoS Biol (2016) 14(2): e1002383.
  6. Spruyt K, Lin JS. The Blind Men and the Elephant: The Risk of Misdiagnosis in Children with Developmental Disabilities. CNS Neurosci Ther (2016) 22(11): 873-874.


  1. Ayub S, Gentet LJ, Fiath R, Schwaerzle M, Borel M, David F, Bartho P, Ulbert I, Paul O, Ruther P. Hybrid intracerebral probe with integrated bare LED chips for optogenetic studies. Biomed Microdevices (2017) 19(3): 49.
  2. Barateau L, Lopez R, Arnulf I, Lecendreux M, Franco P, Drouot X, Leu-Semenescu S, Jaussent I, Dauvilliers Y. Comorbidity between central disorders of hypersomnolence and immune-based disorders. Neurology (2017) 88(1): 93-100.
  3. Bat-Pitault F, Sesso G, Deruelle C, Flori S, Porcher-Guinet V, Stagnara C, Guyon A, Plancoulaine S, Adrien J, Da Fonseca D, Patural H, Franco P. Altered sleep architecture during the first months of life in infants born to depressed mothers. Sleep Med (2017) 30: 195-203.
  4. Farca Luna AJ, Perier M, Seugnet L. Amyloid Precursor Protein in Drosophila Glia Regulates Sleep and Genes Involved in Glutamate Recycling. J Neurosci (2017) 37(16): 4289-4300.
  5. Fernandez LMJ, Comte JC, Le Merre P, Lin JS, Salin PA, Crochet S. Highly Dynamic Spatiotemporal Organization of Low-Frequency Activities During Behavioral States in the Mouse Cerebral Cortex. Cereb Cortex (2017) 27(12): 5444-5462.
  6. Franco P, Bourdin H, Braun F, Briffod J, Pin I, Challamel MJ. [Overnight polysomnography versus respiratory polygraphy in the diagnosis of pediatric obstructive sleep apnea]. Arch Pediatr (2017) 24 Suppl 1: S16-S27.
  7. Franco P, Seailles T, Vecchierini MF. [Why is a special issue on obstructive sleep apnea-hypopnea syndrome in children necessary?]. Arch Pediatr (2017) 24 Suppl 1: S1.
  8. Gillioen B, Plancoulaine S, Montemitro E, Flori S, Lin JS, Guyon A, Stagnara C, Bat-Pitault F, Patural H, Gustin MP, Franco P. Maturation of arousals during day and night in infants with non-smoking and smoking mothers. Early Hum Dev (2017) 115: 46-50.
  9. Guyon A, Morselli LL, Balbo ML, Tasali E, Leproult R, L'Hermite-Baleriaux M, Van Cauter E, Spiegel K. Effects of Insufficient Sleep on Pituitary-Adrenocortical Response to CRH Stimulation in Healthy Men. Sleep (2017) 40(6)
  10. Keijzer H, Spruyt K, Smits MG, de Geest A, Curfs LMG. Can dim light melatonin onset be predicted by the timing of sleep in patients with possible circadian sleep-wake rhythm disorders? Biol Rhythm Res (2017) 48(4): 557-566.
  11. Kong XP, Wang C, Xie JF, Zhao P, Dai LR, Shao YF, Lin JS*, Hou YP*. Neuropeptide S reduces propofol- or ketamine-induced slow wave states through activation of cognate receptors in the rat. Neuropeptides (2017) 63: 59-66.
  12. Lancien M, Inocente CO, Dauvilliers Y, Kugener B, Scholz S, Raverot V, Lin JS, Guyon A, Gustin MP, Franco P. Low cerebrospinal fluid hypocretin levels during sudden infant death syndrome (SIDS) risk period. Sleep Med (2017) 33: 57-60.
  13. Plancoulaine S, Flori S, Bat-Pitault F, Patural H, Lin JS, Franco P. Sleep Trajectories Among Pregnant Women and the Impact on Outcomes: A Population-Based Cohort Study. Matern Child Health J (2017) 21(5): 1139-1146.
  14. Plancoulaine S, Stagnara C, Flori S, Bat-Pitault F, Lin JS, Patural H, Franco P. Early features associated with the neurocognitive development at 36 months of age: the AuBE study. Sleep Med (2017) 30: 222-228.
  15. Putois B, Leslie W, Gustin MP, Challamel MJ, Raoux A, Guignard-Perret A, Weick D, Sauzeau JB, Herbillon V, Zourou F, Spruyt K, Franco P. The French Sleep Disturbance Scale for Children. Sleep Med (2017) 32: 56-65.
  16. Sesso G, Bat-Pitault F, Guyon A, Plancoulaine S, Banfi T, Milioli G, Parrino L, Faraguna U, Franco P. Electrophysiological and microstructural features of sleep in children at high risk for depression: a preliminary study. Sleep Med (2017) 36: 95-103.
  17. Seugnet L, Dissel S, Thimgan M, Cao L, Shaw PJ. Identification of Genes that Maintain Behavioral and Structural Plasticity during Sleep Loss. Front Neural Circuits (2017) 11: 79.
  18. Vaccaro A, Issa AR, Seugnet L, Birman S, Klarsfeld A. Drosophila Clock Is Required in Brain Pacemaker Neurons to Prevent Premature Locomotor Aging Independently of Its Circadian Function. PLoS Genet (2017) 13(1): e1006507.


  1. Aboudhiaf S, Alves G, Parrot S, Amri M, Simonnet MM, Grosjean Y, Maniere G, Seugnet L. LAT1-like transporters regulate dopaminergic transmission and sleep in Drosophila. Sleep (2018) 41(10)
  2. Franco P, Dauvilliers Y, Inocente CO, Guyon A, Villanueva C, Raverot V, Plancoulaine S, Lin JS. Impaired histaminergic neurotransmission in children with narcolepsy type 1. CNS Neurosci Ther (2018) 25(3):386-395
  3. Gouleme N, Debue M, Spruyt K, Vanderveken C, De Siati RD, Ortega-Solis J, Petrossi J, Wiener-Vacher S, Bucci MP, Ionescu E, Thai-Van H, Deggouj N. Changes of spatial and temporal characteristics of dynamic postural control in children with typical neurodevelopment with age: Results of a multicenter pediatric study. Int J Pediatr Otorhinolaryngol (2018) 113: 272-280.
  4. Lin JS, Roussel B, Gaspar A, Zhao Y, Hou Y, Schmidt M, Jouvet A, Jouvet M. The unfinished journey with modafinil and discovery of a novel population of modafinil-immunoreactive neurons. Sleep Med (2018) 49:40-52
  5. Mancini J, Dubus JC, Jouve E, Roux JC, Franco P, Lagrue E, Castelnau P, Cances C, Chaix Y, Rougeot-Jung C, Cornu C, Desportes V, Vallee L, Bahi-Buisson N, Truillet R, Attolini L, Villard L, Blin O, Micallef J. Effect of desipramine on patients with breathing disorders in RETT syndrome. Ann Clin Transl Neurol (2018) 5(2): 118-127.
  6. Pateron B, Marianowski R, Monteyrol PJ, Couloigner V, Akkari M, Chalumeau F, Fayoux P, Leboulanger N, Franco P, Mondain M. French Society of ENT (SFORL) guidelines (short version) on the roles of the various treatment options in childhood obstructive sleep apnea-hypopnea syndrome. Eur Ann Otorhinolaryngol Head Neck Dis (2018) 135(4): 265-268.
  7. Rahman SA, St Hilaire MA, Gronfier C, Chang AM, Santhi N, Czeisler CA, Klerman EB, Lockley SW. Functional decoupling of melatonin suppression and circadian phase resetting in humans. J Physiol (2018) 596(11): 2147-2157.
  8. Spruyt K, Alaribe CU, Nwabara OU. Associations between changes in sleep and body composition in African American children. Sleep Med Dis Int J (2018) 2(4): 69-76.
  9. Sun W, Li SX, Jiang Y, Xu X, Spruyt K, Zhu Q, Tseng CH, Jiang F. A Community-Based Study of Sleep and Cognitive Development in Infants and Toddlers. J Clin Sleep Med (2018) 14(6): 977-984.
  10. Sun W, Li SX, Wang G, Dong S, Jiang Y, Spruyt K, Ling J, Zhu Q, Lee TM, Jiang F. Association of Sleep and Circadian Activity Rhythm with Emotional Face Processing among 12-month-old Infants. Sci Rep (2018) 8(1): 3200.
  11. Thiesse L, Rudzik F, Spiegel K, Leproult R, Pieren R, Wunderli J-M, Foraster M, Héritier H, Eze IC, Vienneau D, Meyer M, Brink M, Probst-Hensch N, Röösli M, Cajochen C. Adverse impact of nocturnal transportation noise on glucose regulation in healthy young adults: effect of different noise scenarios. Environ Int (2018)
  12. Vodovar D, Duchene A, Wimberley C, Leroy C, Pottier G, Dauvilliers Y, Giaume C, Lin JS, Mouthon F, Tournier N, Charveriat M. Cortico-Amygdala-Striatal Activation by Modafinil/Flecainide Combination. Int J Neuropsychopharmacol (2018) 21(7): 687-696.



  1. Daguet I, Bouhassira D, Gronfier C. Pupil size is not a reliable biomarker of subjective sleepiness. Front Neurol (2019): doi: 10.3389/fneur.2019.00108 
  2. Franco P, Guyon A, C Stagnara, S Flori, Bat-Pitault, Lin JS, Patural H, Plancoulaine S, Early polysomnographic characteristics associated with neurocognitive development at 36 months of age, Sleep Medicine, (2019), in press.
  3. Gobert F, Luaute J, Raverot V, Cotton F, Dailler F, Claustrat B, Perrin F, Gronfier C. Is circadian rhythmicity a prerequisite to coma recovery? Circadian recovery concomitant to cognitive improvement in two comatose patients. J Pineal Res (2019): e12555.
  4. Labrèche F, Guénel P, Lévi F, Doré JF, Costa G, Lasfargues G, Gronfier C. on behalf of the Working Group on "Assessment of the health risks for professionals exposed to atypical working hours, especially night work”, French Agency for Food, Environmental and Occupational Health & Safety. Night Shift Work Increases Cancer Risk of Women—Letter. Cancer Epidem Biomar Prev (2019);28:422
  5. Largo R, Lopes MC, Spruyt K, Guilleminault C, Wang YP, Rosa A. Visual and automatic classification of the cyclic alternating pattern in electroencephalography during sleep. Brazilian Journal of Medical and Biological Research Braz J Med Biol Res. 2019 Feb 25;52(3):e8059
  6. Lopes MC, Spruyt K, Azevedo-Soster L, Rosa A, Guilleminault C. Reduction in Parasympathetic Tone During Sleep in Children With Habitual Snoring. Front Neurosci. (2019);12:997. doi: 10.3389/fnins.2018.00997.
  7. Prayag AS, Najjar RP, Gronfier C. Melatonin suppression is exquisitely sensitive to light and primarily driven by melanopsin in humans. J Pineal Res (2019):e12562.
  8. Prayag AS, Jost S, Avouac P, Dumortier D, Gronfier C. Dynamics of non-visual responses in humans: as fast as lightning? Front Neurosci (2019):doi: 10.3389/fnins.2019.00126
  9. Shao YF, Lin JS, Hou YP, The paraventricular thalamus as a major thalamic structure for wake control, Neuroscience Bulletin, (2019), Mar 16. doi: 10.1007/s12264-019-00364-x
  10. Spruyt K, Herbillon V, Putois B, Franco P, Lachaux JP. Mind-wandering, or the allocation of attentional resources, is sleep-driven across childhood. Sci Rep. (2019) Feb 4;9(1):1269.
  11. Urbain N, Fourcaud-Trocmé N, Salin PA, Gentet LJ Brain state dependent modulation of neuronal firing and membrane potential dynamics in the somatosensory thalamus during natural sleep. Cell Reports (2019) Feb 5;26(6):1443-1457.e5.
  12. Botokeky E, Freymond N, Gormand F, Le Cam P, Chatte G, Kuntz J, Liegeon MN, Gaillot-Drevon M, Massardier-Pilonchery A, Fiquemont A, Fort E, Marcu M, Petitjean T, Charbotel B. Benefit of continuous positive airway pressure on work quality in patients with severe obstructive sleep apnea. (2019) Sleep Breath.  Jan 26.