Publications de SLEEP


  1. Chauveau F, Laudereau K, Libourel PA, Gervasoni D, Thomasson J, Poly B, Pierard C, Beracochea D. Ciproxifan improves working memory through increased prefrontal cortex neural activity in sleep-restricted mice. Neuropharmacology (2014) 85: 349-356. [4,249]
  2. Clement O, Valencia Garcia S, Libourel PA, Arthaud S, Fort P, Luppi PH. The inhibition of the dorsal paragigantocellular reticular nucleus induces waking and the activation of all adrenergic and noradrenergic neurons: a combined pharmacological and functional neuroanatomical study. PLoS One (2014) 9(5): e96851. [2,766]


  1. Joseph MA, Fraize N, Ansoud-Lerouge J, Sapin E, Peyron C, Arthaud S, Libourel PA, Parmentier R, Salin PA, Malleret G. Differential Involvement of the Dentate Gyrus in Adaptive Forgetting in the Rat. PLoS One (2015) 10(11): e0142065.
  2. Renouard L, Billwiller F, Clement O, Camargo N, Abdelkarim M, Gay N, Scote-Blachon C, Toure R, Libourel PA, Ravassard P, Salvert D, Peyron C, Claustrat B, Leger L, Salin P, Malleret G, Fort P, Luppi PH. The supramammillary nucleus and the claustrum activate the cortex during REM sleep. Sci Adv (2015) 1(3): e1400177.
  3. Urbain N, Salin PA, Libourel PA, Comte JC, Gentet LJ, Petersen CCH. Whisking-Related Changes in Neuronal Firing and Membrane Potential Dynamics in the Somatosensory Thalamus of Awake Mice. Cell Rep (2015) 13(4): 647-656.
  4. Le Barillier L, Leger L, Luppi PH, Fort P, Malleret G, Salin PA. Genetic deletion of melanin-concentrating hormone neurons impairs hippocampal short-term synaptic plasticity and hippocampal-dependent forms of short-term memory. Hippocampus (2015) 25(11): 1361-1373.
  5. Sapin E, Peyron C, Roche F, Gay N, Carcenac C, Savasta M, Levy P, Dematteis M. Chronic Intermittent Hypoxia Induces Chronic Low-Grade Neuroinflammation in the Dorsal Hippocampus of Mice. Sleep (2015) 38(10): 1537-1546.
  6. Varin C, Rancillac A, Geoffroy H, Arthaud S, Fort P, Gallopin T. Glucose Induces Slow-Wave Sleep by Exciting the Sleep-Promoting Neurons in the Ventrolateral Preoptic Nucleus: A New Link between Sleep and Metabolism. J Neurosci (2015) 35(27): 9900-9911.
  7. Arthaud S, Varin C, Gay N, Libourel PA, Chauveau F, Fort P, Luppi PH, Peyron C. Paradoxical (REM) sleep deprivation in mice using the small-platforms-over-water method: polysomnographic analyses and melanin-concentrating hormone and hypocretin/orexin neuronal activation before, during and after deprivation. J Sleep Res (2015) 24(3): 309-319.
  8. Libourel PA, Corneyllie A, Luppi PH, Chouvet G, Gervasoni D. Unsupervised online classifier in sleep scoring for sleep deprivation studies. Sleep (2015) 38(5): 815-828.


  1. Fraize N, Carponcy J, Joseph MA, Comte JC, Luppi PH, Libourel PA, Salin PA, Malleret G, Parmentier R. Levels of Interference in Long and Short-Term Memory Differentially Modulate Non-REM and REM Sleep. Sleep (2016) 39(12): 2173-2188.
  2. Bernard-Valnet R, Yshii L, Queriault C, Nguyen XH, Arthaud S, Rodrigues M, Canivet A, Morel AL, Matthys A, Bauer J, Pignolet B, Dauvilliers Y, Peyron C, Liblau RS. CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice. Proc Natl Acad Sci USA (2016) 113(39): 10956-10961. [9,504]
  3. Ravassard P, Hamieh AM, Joseph MA, Fraize N, Libourel PA, Lebarillier L, Arthaud S, Meissirel C, Touret M, Malleret G, Salin PA. REM Sleep-Dependent Bidirectional Regulation of Hippocampal-Based Emotional Memory and LTP. Cereb Cortex (2016) 26(4): 1488-1500.
  4. Varin C, Arthaud S, Salvert D, Gay N, Libourel PA, Luppi PH, Leger L, Fort P. Sleep architecture and homeostasis in mice with partial ablation of melanin-concentrating hormone neurons. Behav Brain Res (2016) 298: 100-110.


  1. Billwiller F, Renouard L, Clement O, Fort P, Luppi PH. Differential origin of the activation of dorsal and ventral dentate gyrus granule cells during paradoxical (REM) sleep in the rat. Brain Struct Funct (2017) 222(3): 1495-1507.
  2. Luppi PH, Billwiller F, Fort P. Selective activation of a few limbic structures during paradoxical (REM) sleep by the claustrum and the supramammillary nucleus: evidence and function. Curr Opin Neurobiol (2017) 44: 59-64.
  3. Koike BDV, Farias KS, Billwiller F, Almeida-Filho D, Libourel PA, Tiran-Cappello A, Parmentier R, Blanco W, Ribeiro S, Luppi PH, Queiroz CM. Electrophysiological Evidence That the Retrosplenial Cortex Displays a Strong and Specific Activation Phased with Hippocampal Theta during Paradoxical (REM) Sleep. J Neurosci (2017) 37(33): 8003-8013.
  4. Valencia Garcia S, Libourel PA, Lazarus M, Grassi D, Luppi PH, Fort P. Genetic inactivation of glutamate neurons in the rat sublaterodorsal tegmental nucleus recapitulates REM sleep behaviour disorder. Brain (2017) 140(2): 414-428.


  1. Barrillot B, Roux J, Arthaud S, Averty L, Clair A, Herrel A, Libourel PA. Intramuscular Administration of Ketamine-Medetomidine Assures Stable Anaesthesia Needed for Long-Term Surgery in the Argentine Tegu Salvator Merianae. J Zoo Wildl Med (2018) 49(2): 291-296.
  2. Libourel PA, Barrillot B, Arthaud S, Massot B, Morel AL, Beuf O, Herrel A, Luppi PH. Partial homologies between sleep states in lizards, mammals, and birds suggest a complex evolution of sleep states in amniotes. PLoS Biol (2018) 16(10): e2005982.
  3. Valencia Garcia S, Brischoux F, Clement O, Libourel PA, Arthaud S, Lazarus M, Luppi PH, Fort P. Ventromedial medulla inhibitory neuron inactivation induces REM sleep without atonia and REM sleep behavior disorder. Nat Commun (2018) 9(1): 504.
  4. Dauvilliers Y, Schenck CH, Postuma RB, Iranzo A, Luppi PH, Plazzi G, Montplaisir J, Boeve B. REM sleep behaviour disorder. Nat Rev Dis Primers (2018) 4:19.
  5. Roman A, Meftah S, Arthaud S, Luppi PH, Peyron C. The inappropriate occurrence of rapid eye movement sleep in narcolepsy is not due to a defect in homeostatic regulation of rapid eye movement sleep. Sleep (2018) 41(6)
  6. Varin C, Luppi PH, Fort P. Melanin-concentrating hormone-expressing neurons adjust slow-wave sleep dynamics to catalyze paradoxical (REM) sleep. Sleep (2018) 41(6)
  7. Peyron C, Rampon C, Petit JM, Luppi PH. Sub-regions of the dorsal raphe nucleus receive different inputs from the brainstem. Sleep Med (2018) 49: 53-63.
  8. Valencia Garcia S, Luppi PH, Fort P. A particular medullary-spinal inhibitory pathway is recruited for the expression of muscle atonia during REM sleep. J Exp Neurosci (2018) 12


  1. Massot B, Arthaud S, Barrillot B, Roux J, Ungurean G, Luppi PH, Rattenborg NC, Libourel PA. ONEIROS, a new miniature standalone device for recording sleep electrophysiology, physiology, temperatures and behavior in the lab and field. J Neurosci Meths (2019) 316: 103-116.
  2. Urbain N, Fourcaud-Trocmé N, Laheux S, Salin PA, Gentet LJ. Brain-state-dependent modulation of neuronal firing and membrane potential dynamics in the somatosensory thalamus during natural sleep. Cell Rep (2019) 26: 1443-1447.
  3. Billwiller F, Castillo L, Elseedy H, Ivanov AI, Scapula J, Ghestem A, Carponcy J. Libourel PA, Bras H, Abdelmeguid NE, Krook-Magnuson E, Soltesz I, Bernard C, Luppi PH, Esclapez M. The GABA-Glutamate supramammillary–dorsal Dentate Gyrus pathway controls theta and gamma oscillations in the DG during paradoxical sleep. BioRxiv (2019)
  4. Ungurean G, Rattenborg NC. Neuroethology: Fur seals don't lose sleep over REM lost at sea. Curr Biol (2019) 28: R695–717 (dispatch)