Research areas:
● Central mechanisms responsible for wake maintenance, focus on histaminergic & orexinergic neurons;
● Animal models of experimental sleep & sleep disorders: narcolepsy, sleep apnea, sleepiness of various causes;
● Therapeutic concepts for sleep disorders, focus on wake-promoting agants : Modafinil & H3-receptor inverse agonists such as Pitolisant.
Models & approaches:
● Chronic EEG & sleep-wake recordings & monitoring in freely-moving cats & mice;
● Various pharmacological & behavioral tests in normal & trangenic animals;
● Neuroanatomy: immunohistochemistry & in situ hybridization;
● Pre-clinical assays.
Scientific production
106 articles in international peer-reviewed journals, such as:
PNAS, TiPs, Sleep Med Rev, J Neurosci, Neuropsychopharmacol.
PubMed https://pubmed.ncbi.nlm.nih.gov
GoogleScholar http://scholar.google.fr/citations?user=g2hb9voAAAAJ&hl=fr;
ReseachGate https://www.researchgate.net/profile/Jian_Sheng_Lin;
Publons https://publons.com/researcher/2635315/jian-sheng-lin/
Loop https://loop.frontiersin.org/people/15613/overview
Orcid https://orcid.org/0000-0002-2004-6079
Other links:
Mini CV http://icoprem.univ-lyon1.fr/html/Lin/mini%20CV%202021.htm
Lab link http://icoprem.univ-lyon1.fr/4-laboratoire41-crnl-waking-team-integrative-physiology-of-the-brain-arousal-systems.html
里昂中法学院 Institut Franco-Chinois http://www.institut-franco-chinois-lyon.com/
