Invited talk - "Piriform cortex under the scope : population dynamics and modulation by respiratory features"

Abstract

While respiration is crucial for survival by its peripheral action, it also shares strong functional links with the brain. On the one hand, respiratory patterns are modulated by sensory stimuli, attention, emotions, and can be affected in the case of cognitive disorders. On the other hand, respiration shapes brain function, influencing perception, emotions and cognition. Because of the importance of this intricate brain-body relationship, monitoring respiration in freely moving animals is central to understand neuronal network function in naturalistic conditions. Our team is interested in olfactory information processing in the piriform cortex of mice and its link with respiratory activity.
During this presentation, I will show how the precision of the respiratory signal obtained in mice equipped with portable intra-nasal pressure sensors, when combined with multi-electrode recordings, can provide a detailed description a the respiration dynamics across brain states (sleep states and wake) which can impose temporal constraints on the mechanisms involved in olfactory information processing.
I will then present preliminary data describing piriform cortex network dynamics and its links with respiration. In the last part of my talk, I will show how the internal dynamics of piriform populations is shaped by endogenous of cannabinoid-1 receptor activity, adjusting the balance between sensory evoked and memory-related processes.

Lisa Roux from the Interdisciplinary Institute for Neuroscience in Bordeaux (https://www.iins.u-bordeaux.fr/ROUX#news)

If you are interested in one (or all) of these topics: respiration, multi-electrode unit recordings, olfaction or cannabinoid-1 receptor activity and memory-related processes, please feel free and welcome to join us in the Amphitheater!